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LCH-7749944

SKU: orb1309493

Description

LCH-7749944 (GNF-PF-2356) is a potent PAK4 inhibitor (IC50 = 14.93 µM) that suppresses human gastric cancer cell proliferation by targeting the PAK4/c-Src/EGFR/cyclin D1 pathway and induces apoptosis. This small molecule is a useful research tool for studying oncogenic signaling and cell cycle mechanisms in vitro.

Research Area

Cell Biology, Signal Transduction

Images & Validation

Key Properties

CAS Number796888-12-5
MW350.41
Purity99.28% (May vary between batches)
FormulaC20H22N4O2
SMILESCOc1cccc(Nc2nc(NCC3CCCO3)c3ccccc3n2)c1
TargetApoptosis,PAK
SolubilityDMSO:250 mg/mL (713.45 mM);10% DMSO+40% PEG300+5% Tween 80+45% Saline:5 mg/mL (14.27 mM)

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

Apoptosis, apoptosis, cancer, c-Src, cyclin, cells, EGFR, human, GNF-PF 2356, GNF-PF2356, GNF-PF-2356, Inhibitor, gastric, LCH 7749944, LCH7749944, LCH-7749944, inhibit, PAK4, PAK, p21 activated kinases, proliferation

Similar Products

  • LCH-7749944 [orb1219723]

    >98% (HPLC)

    796888-12-5

    350.41

    C20H22N4O2

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LCH-7749944 (orb1309493)

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Available Sizes

Select a size below

2 mg
$ 80.00
5 mg
$ 110.00
1 ml x 10 mM (in DMSO)
$ 120.00
10 mg
$ 140.00
25 mg
$ 220.00
50 mg
$ 310.00
100 mg
$ 430.00
DispatchUsually dispatched within 3-5 working days
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