Levamlodipine

SKU: orb1227112

Description

Amlodipine is a synthetic dihydropyridine and a calcium channel blocker with antihypertensive and antianginal properties. Amlodipine inhibits the influx of extracellular calcium ions into myocardial and peripheral vascular smooth muscle cells, thereby preventing vascular and myocardial contraction. This results in a dilatation of the main coronary and systemic arteries, decreased myocardial contractility, increased blood flow and oxygen delivery to the myocardial tissue, and decreased total peripheral resistance. This agent may also modulate multi-drug response (MDR) activity through inhibition of the p-glycoprotein efflux pump.

Research Area

Pharmacology & Drug Discovery

Key Properties

• CAS Number: 103129-82-4
• MW: 408.88
• Purity: >98% (HPLC)
• Formula: C₂₀H₂₅N₂O₅Cl
• SMILES: O=C(C1=C(COCCN)NC(C)=C(C(OC)=O)[C@@H]1C2=CC=CC=C2Cl)OCC
• Target: Calcium Channel
• Solubility: DMSO: 10 mM

Storage & Handling

• Storage: Storage temperature: -20°C. Stability: ≥ 2 years
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Levamlodipine | S-Amlodipine |

Quick Database Links

Gene Symbol

Calcium Channel