Levothyroxine sodium

SKU: orb1219275

Description

Levothyroxine, the major hormone derived from the thyroid gland, is the agonist of Thyroid hormone receptor alpha and beta.evothyroxine (L-T(4))can upregulate the expression of P-gp mRNA and protein in LS180 cells, but only L-T(4) and L-T(3) can produce the same effect in Caco-2 cells, which are relatively lacking in PXR.

Research Area

Pharmacology & Drug Discovery

Key Properties

• CAS Number: 55-03-8
• MW: 798.85
• Purity: >98% (HPLC)
• Formula: C₁₅H₁₀I₄NO₄.Na
• SMILES: N[C@@H](CC1=CC(I)=C(OC2=CC(I)=C(O)C(I)=C2)C(I)=C1)C(O[Na])=O
• Target: Thyroid Hormone
• Solubility: DMSO:100 mg/ml (125.18 mM)

Storage & Handling

• Storage: Storage temperature: -20°C. Stability: ≥ 2 years
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

L-T4 sodium,L-Thyroxine sodium,LT4 sodium

Quick Database Links

Gene Symbol

Thyroid Hormone