Linopirdine

SKU: orb1308125

Description

Linopirdine (DuP 996) is a selective M-type potassium channel (Kv7/KCNQ) inhibitor and a TRPV1 agonist. This orally active cognitive enhancer stimulates the release of acetylcholine and other neurotransmitters, making it a useful research tool for studying synaptic transmission and cognitive function in both in vitro and in vivo neurological models.

Research Area

Pharmacology & Drug Discovery

Key Properties

• CAS Number: 105431-72-9
• MW: 391.46
• Purity: 99.45% (May vary between batches)
• Formula: C₂₆H₂₁N₃O
• SMILES: O=C1N(c2ccccc2C1(Cc1ccncc1)Cc1ccncc1)c1ccccc1
• Target: TRP/TRPV Channel,Potassium Channel
• Solubility: 10% DMSO+40% PEG300+5% Tween 80+45% Saline:4 mg/mL (10.22 mM);DMSO:110 mg/mL (281 mM)

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

DuP 996, DuP996, DuP-996, current, cognition, Channels, acetylcholine, enhancing, Inhibitor, Linopirdine, Kv7, KcsA, KCNQ, inhibit, M-type, M-type K+ current, orally, PotassiumChannel, Potassium Channel, TRP Channel, Transient receptor potential channels, TRPV1, TRPV Channel, TRPVChannel, TRPChannel

Quick Database Links

Gene Symbol

TRP/TRPV Channel,Potassium Channel