Liothyronine

SKU: orb1307879

Description

Liothyronine (T3) is a potent synthetic agonist of thyroid hormone receptors TRα and TRβ (Ki = 2.33 nM). It is widely used in research to study thyroid hormone signaling, metabolic regulation, and to establish hyperthyroidism models in both in vitro and in vivo experimental systems.

Research Area

Metabolism Research, Pharmacology & Drug Discovery

Key Properties

• CAS Number: 6893-02-3
• MW: 650.97
• Purity: 98.61% (May vary between batches)
• Formula: C₁₅H₁₂I₃NO₄
• SMILES: O(C1=C(I)C=C(C[C@@H](C(O)=O)N)C=C1I)C2=CC(I)=C(O)C=C2
• Target: Thyroid hormone receptor(THR),Endogenous Metabolite
• Solubility: DMSO:3.25 mg/mL (4.99 mM);10% DMSO+40% PEG300+5% Tween 80+45% Saline:4.95 mg/mL (7.6 mM)

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

EndogenousMetabolite, Endogenous Metabolite, L-3,3',5-Triiodothyronine, Lyothyronine, 3,3',5-Triiodo-L-thyronine, TRα, TRβ, Tresitope, Triiodothyronine, T3, T-3, T 3, Thyroid hormone receptor(THR), Thyroidhormonereceptor, Thyroidhormonereceptor(THR), Thyroid hormone receptor, thyroid hormone, THR

Quick Database Links

Gene Symbol

Thyroid hormone receptor(THR),Endogenous Metabolite