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LM22B-10

SKU: orb1223143

Description

LM22B-10 is a TrkB and TrkC agonist. LM22B-10 exhibits neurotrophic activity (EC50 = 200-300 nM). LM22B-10 improves survival and increases neurite outgrowth in hippocampal cells in vitro. LM22B-10 increased cell survival and strongly accelerated neurite outgrowth, superseding the effects of brain-derived neurotrophic factor (BDNF), NT-3 or the two combined.

Images & Validation

Key Properties

CAS Number342777-54-2
MW485.01
Purity>98% (HPLC)
FormulaC27H33ClN2O4
SMILESClc1ccc(cc1)C(c2ccc(cc2)N(CCO)CCO)c3ccc(cc3)N(CCO)CCO
TargetSyk
SolubilityDMSO : ≥ 150 mg/mL; 309.27 mM

Storage & Handling

StorageStorage temperature: -20°C. Stability: ≥ 2 years
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

LM22B-10 | LM22B 10 | LM22B10

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  • LM22B-10 [orb1302812]

    98.18% (May vary between batches)

    342777-54-2

    485.01

    C27H33ClN2O4

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LM22B-10 (orb1223143)

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200 mg
500 mg
2 mg
$ 150.00
5 mg
$ 220.00
10 mg
$ 350.00
25 mg
$ 780.00
50 mg
$ 1,160.00
100 mg
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