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Loureirin A

SKU: orb1221323

Description

Loureirin A has an inhibitory effect on platelet activation perhaps through an impairment of PI3K/Akt signaling.Loureirin A negatively affects agonist-induced platelet aggregation such as collagen collagen-related peptide (CRP) ADP and thrombin. Loureirin A activates Wnt/-catenin pathway and promotes hair follicle stem cells (FSCs)-seeded tissue-engineered skin to repair skin wound.The molecular mechanism of Loureirin A and Wnt signaling pathway mediated anti- hepatic fibrosis and anti- angiogenesis may involve down- regulation the expression of Frizzled- 4inhibiting the synthesis and secretion of α- SMATGF- β1and the proliferation of HSCs.

Images & Validation

Key Properties

CAS Number119425-89-7
MW286.32
Purity>98% (HPLC)
FormulaC17H18O4
SMILESCOc1ccc(CCC(=O)c2ccc(O)cc2)c(OC)c1
TargetPI3K
SolubilityDMSO: ≥ 86.6 mg/mL (302.46 mM)

Storage & Handling

StorageStorage temperature: -20°C. Stability: ≥ 2 years
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

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Loureirin A (orb1221323)

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