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LP-211

SKU: orb1301833

Description

LP-211 is a potent and selective 5-HT7 receptor agonist with high brain penetrance, exhibiting a Ki of 0.58 nM and over 300-fold selectivity versus the 5-HT1A receptor. This tool compound is widely used in neuroscience research to investigate the receptor's role in circadian rhythms, learning, and mood, utilizing both in vitro binding assays and in vivo behavioral models.

Research Area

Neuroscience, Pharmacology & Drug Discovery

Images & Validation

Key Properties

CAS Number1052147-86-0
MW466.62
Purity98.65% (May vary between batches)
FormulaC30H34N4O
SMILESC(CCCCC(NCC1=CC=C(C#N)C=C1)=O)N2CCN(C3=C(C=CC=C3)C4=CC=CC=C4)CC2
Target5-HT Receptor,Dopamine Receptor
SolubilityDMSO:90 mg/mL (192.88 mM);10% DMSO+40% PEG300+5% Tween 80+45% Saline:3.3 mg/mL (7.07 mM)

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

5-HT7, 5HT Receptor, 5HTReceptor, 5-hydroxytryptamine Receptor, 5-HT1A, 5-HT Receptor, D2, Dopamine Receptor, DopamineReceptor, inhibit, Inhibitor, LP 211, LP211, LP-211, Serotonin Receptor

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LP-211 (orb1301833)

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Available Sizes

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100 mg
200 mg
2 mg
$ 80.00
1 ml x 10 mM (in DMSO)
$ 110.00
5 mg
$ 110.00