LP-261

SKU: orb1297994

Description

LP-261 is a colchicine-site tubulin inhibitor that arrests the cell cycle at the G2/M phase. It is a research tool for studying cytoskeleton dynamics and mechanisms of antimitotic agents in both in vitro cell-based assays and in vivo preclinical cancer models.

Research Area

Signal Transduction

Key Properties

• CAS Number: 915412-67-8
• MW: 421.47
• Purity: 99.76% (May vary between batches)
• Formula: C₂₂H₁₉N₃O₄S
• SMILES: COc1cc(ccn1)C(=O)c1cc(NS(C)(=O)=O)cc(c1)-c1cccc2[nH]ccc12
• Target: Microtubule Associated
• Solubility: DMSO:22 mg/mL (52.2 mM)

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

cancer, BXPC-3, anti-mitotic, NCI-H522, MicrotubuleAssociated, Microtubule/Tubulin, Microtubule Associated, Jurkat, inhibit, LP261, LP-261, LP 261, H522, Inhibitor, MCF-7, SW-620, tubulin polymerization, tumor

Quick Database Links

Gene Symbol

Microtubule Associated