LY518674

SKU: orb1308094

Description

LY518674 is a potent and selective PPARα agonist (EC50 = 42 nM for human PPARα) used in atherosclerosis research. It modulates lipid metabolism by lowering triglycerides and raising HDL-C, making it a valuable tool for in vitro and in vivo studies of cardiovascular disease and metabolic disorders.

Research Area

Metabolism Research, Molecular Biology

Key Properties

• CAS Number: 425671-29-0
• MW: 409.48
• Purity: 98.87% (May vary between batches)
• Formula: C₂₃H₂₇N₃O₄
• SMILES: Cc1ccc(Cn2[nH]c(CCCc3ccc(OC(C)(C)C(O)=O)cc3)nc2=O)cc1
• Target: PPAR
• Solubility: 10% DMSO+40% PEG300+5% Tween 80+45% Saline:5 mg/mL (12.21 mM);DMSO:250 mg/mL (610.53 mM)

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

atherosclerosis, human PPARα, LY674, LY-674, LY-518674, LY518674, LY 518674, LY 674, Inhibitor, inhibit, Peroxisome proliferator-activated receptors, PPAR, PPARα

Quick Database Links

Gene Symbol

PPAR