MDR-652

SKU: orb1305977

Description

MDR-652 is a potent, nonpungent TRPV1 agonist with high affinity (Ki: 11.4 nM hTRPV1) and functional potency (EC50: 5.05 nM hTRPV1). Its strong topical analgesic properties support research in pain pathways, inflammation, and neurobiology, applicable in both in vitro receptor studies and in vivo models of nociception.

Research Area

Pharmacology & Drug Discovery

Key Properties

• CAS Number: 1933528-96-1
• MW: 447.95
• Purity: 95.04% (May vary between batches)
• Formula: C₂₂H₂₃ClFN₃O₂S
• SMILES: CC(C)(C)c1nc(c(CNC(=O)Nc2ccc(CO)c(F)c2)s1)-c1cccc(Cl)c1
• Target: TRP/TRPV Channel
• Solubility: 10% DMSO+40% PEG300+5% Tween 80+45% Saline:5 mg/mL (11.16 mM);DMSO:249 mg/mL (555.87 mM)

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

activity, analgesic, MDR 652, MDR652, MDR-652, hTRPV1, ligand, Inhibitor, inhibit, pain, neuropathic, Transient receptor potential channels, TRP Channel, TRPChannel, TRPV Channel, TRPV1, TRPVChannel

Quick Database Links

Gene Symbol

TRP/TRPV Channel