Mibefradil dihydrochloride

SKU: orb1309424

Description

Mibefradil dihydrochloride is a calcium channel blocker exhibiting moderate selectivity for T-type over L-type channels (IC50s of 2.7 μM and 18.6 μM, respectively). It is a research tool used in cardiovascular and neurological studies, with applications in both in vitro electrophysiology and in vivo models of hypertension and arrhythmia.

Research Area

Metabolism Research, Pharmacology & Drug Discovery

Key Properties

• CAS Number: 116666-63-8
• MW: 568.55
• Purity: 98.66% (May vary between batches)
• Formula: C₂₉H₄₀Cl₂FN₃O₃
• SMILES: Cl.Cl.COCC(=O)O[C@]1(CCN(C)CCCc2nc3ccccc3[nH]2)CCc2cc(F)ccc2[C@@H]1C(C)C
• Target: Calcium Channel
• Solubility: H2O:122 mg/mL (214.58 mM)

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Ca channels, Ca2+ channels, Calcium Channel, CalciumChannel, Inhibitor, inhibit, Mibefradil, Mibefradil dihydrochloride, Mibefradil Dihydrochloride, L-type calcium channel, T-type calcium channel, Ro 40-5967, Ro 40-5967 (dihydrochloride)

Quick Database Links

Gene Symbol

Calcium Channel