Mitraphylline

SKU: orb1297280

Description

Mitraphylline is a natural indole alkaloid with demonstrated anti-proliferative activity against human glioma and neuroblastoma cell lines in vitro. It also exhibits anti-inflammatory properties by inhibiting LPS-induced activation of primary human neutrophils, supporting research in oncology and immunology.

Research Area

Cell Biology, Immunology & Inflammation, Signal Transduction

Key Properties

• CAS Number: 509-80-8
• MW: 368.43
• Purity: 99.89% (May vary between batches)
• Formula: C₂₁H₂₄N₂O₄
• SMILES: [H][C@@]12C[C@]3([H])C(=CO[C@@H](C)[C@@]3([H])CN1CC[C@]21C(=O)Nc2ccccc12)C(=O)OC
• Target: TNF,IL Receptor,NF-κB,Interleukin
• Solubility: DMSO:6.76 mg/mL (18.35 mM)

Storage & Handling

• Storage: Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Inhibitor, ILReceptor, IL Receptor, inhibit, Mitraphylline, NF-κB, NF-kB, NFkB, NFκB, TNF-α, tomentosa, Uncaria

Quick Database Links

Gene Symbol

TNF,IL Receptor,NF-κB,Interleukin