MK-2206

SKU: orb1306994

Description

MK-2206 2HCl is a potent, selective, and orally bioavailable allosteric inhibitor of Akt isoforms (Akt1/2/3). It demonstrates antitumor efficacy in preclinical models and is utilized in cancer research for studying PI3K/Akt signaling in both cellular and animal studies.

Research Area

Cell Biology

Key Properties

• CAS Number: 1032350-13-2
• MW: 480.39
• Purity: >98%
• Formula: C₂₅H₂₁N₅O·2HCl
• SMILES: Cl.Cl.NC1(CCC1)c1ccc(cc1)-c1nc2ccn3c(n[nH]c3=O)c2cc1-c1ccccc1
• Target: Kinase
• Solubility: Soluble in DMSO ( up to 10 mg/ml with warming)

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

breast, Akt, Autophagy, Akt2, Akt3, Akt1, Apoptosis, cancer, oral, MK 2206, MK 2206 Dihydrochloride, MK 2206 dihydrochloride, MK2206, MK-2206, MK-2206 (2HCl), MK-2206 2HCl, MK2206 dihydrochloride, MK2206 Dihydrochloride, MK-2206 Dihydrochloride, Inhibitor, inhibit, loss, mutant, PIK3CA, PKB, sensitive, selective, Protein kinase B, PTEN

Quick Database Links

Gene Symbol

Kinase