ML-180

SKU: orb1309410

Description

ML-180 (SR1848) is a potent small molecule inverse agonist of the orphan nuclear receptor LRH-1 (NR5A2), exhibiting an IC50 of 3.7 µM. This compound is a valuable research tool for studying LRH-1's role in metabolism, inflammation, and cancer in both cellular and animal models.

Research Area

Pharmacology & Drug Discovery

Key Properties

• CAS Number: 863588-32-3
• MW: 388.89
• Purity: 99.74% (May vary between batches)
• Formula: C₂₀H₂₅ClN₄O₂
• SMILES: Clc1cccc(c1)N1CCN(CC1)c1cc(=O)n(C2CCCCC2)c(=O)[nH]1
• Target: Others,Orphan Receptor
• Solubility: DMSO:11 mg/mL (28.29 mM)

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

cancers, factor-1, Inhibitor, homolog, inhibit, NR5A2, NR5A1, liver, nuclear, Orphan, orphan nuclear receptor NR5A2, LRH-1, ML180, ML-180, ML 180, SF-1, receptor, SR1848, SR-1848, SR 1848, steroidogenic

Quick Database Links

Gene Symbol

Others,Orphan Receptor