ML241 hydrochloride

SKU: orb1302655

Description

ML241 is a potent and selective p97 ATPase inhibitor, demonstrated to block the degradation of p97-dependent proteasome substrates in cellular assays. This activity provides a rationale for its investigation as a potential chemotherapeutic agent in cancer research, supporting the development of pathway-specific p97 inhibitors for both in vitro and in vivo studies.

Research Area

Protein Biochemistry

Key Properties

• CAS Number: 2070015-13-1
• MW: 408.92
• Purity: 99.91% (May vary between batches)
• Formula: C₂₃H₂₅ClN₄O
• SMILES: Cl.C(Nc1nc(nc2CCCCc12)N1CCOc2ccccc12)c1ccccc1
• Target: p97
• Solubility: DMSO:50 mg/mL (122.27 mM);10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (4.89 mM)

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

inhibit, Inhibitor, p97, ML 241, ML 241 Hydrochloride, ML241, ML-241, ML241 hydrochloride, ML241 Hydrochloride, ML-241 hydrochloride, ML-241 Hydrochloride, Cdc48, VCP

Quick Database Links

Gene Symbol

p97