MMAF-OMe

SKU: orb1309406

Description

MMAF-OMe is a potent antimitotic agent and a key cytotoxin used in antibody-drug conjugates (ADCs). It demonstrates sub-nanomolar cytotoxicity against various cancer cell lines in vitro and is employed in oncology research for evaluating ADC efficacy in both cellular and animal models.

Key Properties

• CAS Number: 863971-12-4
• MW: 745.99
• Purity: 98.15% (May vary between batches)
• Formula: C₄₀H₆₇N₅O₈
• SMILES: CC[C@H](C)[C@@H]([C@@H](CC(=O)N1CCC[C@H]1[C@H](OC)[C@@H](C)C(=O)N[C@@H](Cc1ccccc1)C(=O)OC)OC)N(C)C(=O)[C@@H](NC(=O)[C@@H](NC)C(C)C)C(C)C
• Target: ADC Cytotoxin
• Solubility: 5% DMSO+95% Saline:4 mg/mL (5.36 mM);DMSO:99 mg/mL (132.71 mM)

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

ADC Cytotoxin, ADC Payload, ADCCytotoxin, MMAF OMe, MMAFOMe, MMAF-OMe, inhibit, Monomethyl auristatin F methyl ester, Inhibitor

Quick Database Links

Gene Symbol

ADC Cytotoxin