Mollugin

SKU: orb1222045

Description

Mollugin may be a JAK2 inhibitor and inhibits LPS-induced inflammatory responses by blocking the activation of the JAK-STAT pathway. Mollugin as a candidate for a chemotherapeutic agent in OSCCs via the upregulation of the HO-1 and Nrf2 pathways and the downregulation of NF- κ B. Mollugin may be a novel therapeutic candidate for bone loss-associated disorders including osteoporosis, rheumatoid arthritis, and periodontitis. Also, it has anticancer efficacy, can modulate the HER2 pathway in HER2-overexpressing Y cells with a potential role in the treatment and prevention of human breast and ovarian Y with HER2 overexpression.

Key Properties

• CAS Number: 55481-88-4
• MW: 284.3
• Purity: >98% (HPLC)
• Formula: C₁₇H₁₆O₄
• SMILES: CC1(C=Cc2c(O1)c1ccccc1c(c2C(=O)OC)O)C
• Target: COX
• Solubility: In Vitro: DMSO : 33.33 mg/mL (117.23 mM)

Storage & Handling

• Storage: Storage temperature: -20°C. Stability: ≥ 2 years
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Rubimaillin | Mollugin

Quick Database Links

Gene Symbol

COX