Monomethyl fumarate

SKU: orb1309398

Description

Monomethyl fumarate acts as a potent and selective agonist for the hydroxycarboxylic acid receptor 2 (HCAR2/GPR109A). This small molecule is utilized in research to investigate anti-inflammatory and neuroprotective pathways, with applications in both in vitro cellular assays and in vivo models of autoimmune and neurological diseases.

Research Area

Metabolism Research, Pharmacology & Drug Discovery

Key Properties

• CAS Number: 2756-87-8
• MW: 130.1
• Purity: ≥98% (May vary between batches)
• Formula: C₅H₆O₄
• SMILES: COC(=O)\C=C\C(O)=O
• Target: Drug Metabolite,GPCR
• Solubility: DMSO:55 mg/mL (422.75 mM);H2O:8 mg/mL (61.49 mM);10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (15.37 mM)

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Dimethyl, DMF, DrugMetabolite, Drug Metabolite, neuroprotective, metabolite, Monomethyl fumarate, Monomethyl Fumarate, Monomethyl, inhibit, Inhibitor, HCA2, HCAR2, HM74A, GPR109A, fumarate, retinal, PUMA-G

Quick Database Links

Gene Symbol

Drug Metabolite,GPCR