MRGPRX1 agonist 1

SKU: orb1309392

Description

MRGPRX1 agonist 1 is a potent and selective small molecule activator of the Mas-related G-protein-coupled receptor X1, exhibiting an EC50 of 50 nM. This compound is a valuable research tool for investigating MRGPRX1-mediated signaling in vitro and its role in itch, pain, and allergic responses in preclinical models.

Research Area

Pharmacology & Drug Discovery

Key Properties

• CAS Number: 2377379-39-8
• MW: 435.5
• Purity: 99.59% (May vary between batches)
• Formula: C₂₃H₂₁N₃O₄S
• SMILES: COc1ccccc1S(=O)(=O)Nc1ccc(C)cc1Oc1ccc2c(N)nccc2c1
• Target: MRGPR
• Solubility: DMSO:125 mg/mL (287.03 mM);10% DMSO+40% PEG300+5% Tween 80+45% Saline:4 mg/mL (9.18 mM)

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

inhibit, MRGPRX1, MRGPRX1 agonist 1, MRGPRX-1 agonist 1, Inhibitor

Quick Database Links

Gene Symbol

MRGPR