MSA-2

SKU: orb1298624

Description

MSA-2 is a potent, orally bioavailable non-nucleotide STING agonist. Its non-covalent dimer binds STING with nanomolar affinity, inducing interferon-β secretion and demonstrating robust anti-tumor activity and immune memory in syngeneic mouse models, including synergy with anti-PD-1 therapy.

Research Area

Immunology & Inflammation

Key Properties

• CAS Number: 129425-81-6
• MW: 294.32
• Purity: 97.87% (May vary between batches)
• Formula: C₁₄H₁₄O₅S
• SMILES: COc1cc2cc(sc2cc1OC)C(=O)CCC(O)=O
• Target: STING
• Solubility: DMSO:255 mg/mL (866.4 mM);0.5% CMC-Na:12.5 mg/mL (42.47 mM)

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

MSA 2, MSA2, MSA-2, MPYS, immunity, inhibit, Inhibitor, MITA, ERIS, interferon-β, MC38, secretion, TMEM173, TNF-α, Stimulator of Interferon Genes, STING, tumor

Quick Database Links

Gene Symbol

STING