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Nelociguat

SKU: orb1299984

Description

Nelociguat (BAY60-4552) is a stimulator of soluble guanylate cyclase (sGC), a central enzyme in nitric oxide (NO) signaling. This research compound is used in vitro and in vivo to study cardiovascular and pulmonary diseases, including pulmonary hypertension, by potentiating the NO-sGC-cGMP pathway.

Research Area

Pharmacology & Drug Discovery

Images & Validation

Key Properties

CAS Number625115-52-8
MW408.39
Purity98.00% (May vary between batches)
FormulaC19H17FN8O2
SMILESCOC(=O)Nc1c(N)nc(nc1N)-c1nn(Cc2ccccc2F)c2ncccc12
TargetGuanylate cyclase
SolubilityDMSO:4.09 mg/mL (10.01 mM);10% DMSO+40% PEG300+5% Tween 80+45% Saline:1 mg/mL (2.45 mM)

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

Guanylate cyclase, Guanylatecyclase, Guanylate Cyclase, Inhibitor, inhibit, Nelociguat, BAY60-4552

Similar Products

  • Nelociguat [orb1220488]

    >98% (HPLC)

    625115-52-8

    408.39

    C19H17FN8O2

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Nelociguat (orb1299984)

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Available Sizes

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1 ml x 10 mM (in DMSO)
$ 70.00
10 mg
$ 80.00
25 mg
$ 100.00
50 mg
$ 120.00
100 mg
$ 160.00
500 mg
$ 320.00
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