Nelotanserin

SKU: orb1299895

Description

Nelotanserin (APD125) is a potent and selective inverse agonist of the 5-HT2A receptor (IC50 = 1.7 nM), with moderate activity at 5-HT2C and weak activity at 5-HT2B. It is a valuable research tool for investigating serotonin receptor function in neuropharmacology, sleep disorders, and related in vitro and in vivo studies.

Research Area

Neuroscience, Pharmacology & Drug Discovery

Key Properties

• CAS Number: 839713-36-9
• MW: 437.24
• Purity: 98.01% (May vary between batches)
• Formula: C₁₈H₁₅BrF₂N₄O₂
• SMILES: COc1ccc(NC(=O)Nc2ccc(F)cc2F)cc1-c1c(Br)cnn1C
• Target: 5-HT Receptor
• Solubility: DMSO:250 mg/mL (571.77 mM)

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

5HTReceptor, 5HT Receptor, 5-HT, 5-hydroxytryptamine Receptor, 5-HT Receptor, APD125, APD-125, APD 125, Nelotanserin, inhibit, Inhibitor, Serotonin Receptor

Quick Database Links

Gene Symbol

5-HT Receptor