Nirmatrelvir

SKU: orb1298161

Description

Nirmatrelvir (PF-07321332) is a potent, orally bioavailable inhibitor of the SARS-CoV-2 3CL protease (3CLpro). It is widely used in both in vitro biochemical assays and in vivo animal models to study antiviral mechanisms and therapeutic potential against COVID-19.

Research Area

Infectious Disease & Virology

Key Properties

• CAS Number: 2628280-40-8
• MW: 499.53
• Purity: 98.66% (May vary between batches)
• Formula: C₂₃H₃₂F₃N₅O₄
• SMILES: C(N[C@@H](C[C@H]1C(=O)NCC1)C#N)(=O)[C@@H]2[C@@]3([C@@](C3(C)C)(CN2C([C@@H](NC(C(F)(F)F)=O)[C@](C)(C)C)=O)[H])[H]
• Target: SARS-CoV
• Solubility: DMSO:257.5 mg/mL (515.48 mM);10% DMSO+40% PEG300+5% Tween 80+45% Saline:13 mg/mL (26.02 mM)

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

3CLpro, 3CLPRO, Antiviral, Inhibitor, HIV, inhibit, Nirmatrelvir, PF 07321332, PF-07321332, PF07321332, SARS coronavirus, SARSCoV, SARS-CoV, virus

Quick Database Links

Gene Symbol

SARS-CoV