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Nirogacestat
SKU: orb1300331
Description
Research Area
Cell Biology, Neuroscience, Protein Biochemistry, Stem Cell & Developmental Biology
Images & Validation
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Key Properties
−| CAS Number | 1290543-63-3 |
|---|---|
| MW | 489.64 |
| Purity | 97.98% (May vary between batches) |
| Formula | C27H41F2N5O |
| SMILES | CCC[C@H](N[C@H]1CCc2cc(F)cc(F)c2C1)C(=O)Nc1cn(cn1)C(C)(C)CNCC(C)(C)C |
| Target | Apoptosis,Gamma-secretase |
| Solubility | 10% DMSO+90% Corn Oil:3.3 mg/mL (6.74 mM);Ethanol:90 mg/mL (183.81 mM);H2O:< 1 mg/mL (insoluble or slightly soluble);DMSO:61.25 mg/mL (125.09 mM) |
Storage & Handling
−| Storage | -20°C |
|---|---|
| Expiration Date | 12 months from date of receipt. |
| Disclaimer | For research use only |
Alternative Names
−Apoptosis, cancer, Notch, inhibit, Nirogacestat, gastrointestinal, Inhibitor, Gamma secretase, Gammasecretase, PF 3084014, PF03084014, PF-03084014, PF-3084014, PF3084014, PF 03084014, toxicity, γ-secretase, γ secretase
Similar Products
−PF-03084014 [orb1223350]
>98% (HPLC)
1290543-63-3
489.64
C27H41F2N5O
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Gene Symbol
Apoptosis,Gamma-secretase
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Protocol Information
Nirogacestat (orb1300331)
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