Nodinitib-1

SKU: orb1223978

Description

A potent and selective NOD1 inhibitor with IC50 of 0.56 uM; no inhibition on NOD1, TNFα (IC50> 20 uM) and dIKKγ/NEMO, MYD88, FLIP, CARD6, APAF1 or NLRC4; inhibits IL-8 production induced by NOD1 ligand and γ-tri-DAP-induced expression of the prototypical NF-κB target gene IκBα at the mRNA level.

Key Properties

• CAS Number: 799264-47-4
• MW: 287.3369
• Purity: >98% (HPLC)
• Formula: C₁₄H₁₃N₃O₂S
• SMILES: NC1=NC2=CC=CC=C2N1S(=O)(C3=CC=C(C)C=C3)=OInChI=1S/C14H13N3O2S/c1-10-6-8-11(9-7-10)20(18,19)17-13-5-3-2-4-12(13)16-14(17)15/h2-9H,1H3,(H2,15,16)
• Target: NOD
• Solubility: DMSO: 20 mg/mL

Storage & Handling

• Storage: Storage temperature: -20°C. Stability: ≥ 2 years
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

ML-130 | CID-1088438 | Nodinitib

Quick Database Links

Gene Symbol

NOD