NV-5138

SKU: orb1309310

Description

NV-5138 is a leucine-mimetic, orally bioavailable small molecule that acts as a selective intracerebral mTORC1 agonist via Sestrin2 binding. It serves as a research tool for studying mTOR signaling in the context of depression, with applications in both in vitro and in vivo neurological research models.

Research Area

Signal Transduction

Key Properties

• CAS Number: 2095886-80-7
• MW: 181.18
• Purity: 98.00% (May vary between batches)
• Formula: C₇H₁₃F₂NO₂
• SMILES: CC(C)(C[C@H](N)C(O)=O)C(F)F
• Target: mTOR
• Solubility: DMSO:10.7 mg/mL (59.06 mM)

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Inhibitor, Mammalian target of Rapamycin, NV 5138, NV5138, NV-5138, mTORC1, mTOR, inhibit

Quick Database Links

Gene Symbol

mTOR