Paritaprevir

SKU: orb1305953

Description

Paritaprevir (ABT450) is a potent small molecule inhibitor targeting the HCV NS3/4A serine protease. It demonstrates high antiviral activity with EC50 values of 1 nM against HCV genotype 1a and 0.21 nM against genotype 1b. This compound is a key research tool for studying HCV replication and antiviral mechanisms in biochemical and cellular assays.

Research Area

Infectious Disease & Virology, Pharmacology & Drug Discovery, Protein Biochemistry

Key Properties

• CAS Number: 1216941-48-8
• MW: 765.88
• Purity: 98.04% (May vary between batches)
• Formula: C₄₀H₄₃N₇O₇S
• SMILES: Cc1cnc(cn1)C(=O)N[C@H]1CCCCC\C=C/[C@@H]2C[C@]2(NC(=O)[C@@H]2C[C@H](CN2C1=O)Oc1nc2ccccc2c2ccccc12)C(=O)NS(=O)(=O)C1CC1
• Target: HCV Protease,SARS-CoV
• Solubility: DMSO:80 mg/mL (104.46 mM);10% DMSO+40% PEG300+5% Tween 80+45% Saline:3.3 mg/mL (4.31 mM)

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Ritonavir, SARS coronavirus, SARS-CoV 3CLPpro, SARS-CoV, Veruprevir, 1221573-85-8, ABT450, ABT-450, ABT 450, CYP450, Inhibitor, HCV 1a, HCV 1b, HCV genotype 1a, HCV genotype 1b, HCV, HCVProtease, HCV Protease, HCV NS3/4A, Hepatitis C virus, inhibit, NS3/4A, Paritaprevir, orally active

Quick Database Links

Gene Symbol

HCV Protease,SARS-CoV