PCO371

SKU: orb1307912

Description

PCO371 is a potent and selective small molecule agonist of the parathyroid hormone receptor 1 (PTH1R), demonstrating oral bioavailability. It serves as a research tool for studying bone metabolism and PTH signaling in both cellular assays and animal models.

Research Area

Metabolism Research

Key Properties

• CAS Number: 1613373-33-3
• MW: 635.65
• Purity: 97.17% (May vary between batches)
• Formula: C₂₉H₃₂F₃N₅O₆S
• SMILES: Cc1cc(cc(C)c1CCS(=O)(=O)N1CCC2(CC1)N=C(NC2=O)c1ccc(OC(F)(F)F)cc1)N1C(=O)NC(=O)C1(C)C
• Target: Thyroid hormone receptor(THR)
• Solubility: DMSO:120 mg/mL (188.78 mM);10% DMSO+40% PEG300+5% Tween 80+45% Saline:5 mg/mL (7.87 mM)

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

THR, Thyroid hormone receptor, Thyroidhormonereceptor(THR), Thyroidhormonereceptor, thyroid hormone receptor-1 (PTHR1), Thyroid Hormone Receptor, Thyroid hormone receptor(THR), PTHR1, Inhibitor, inhibit, PCO 371, PCO371, PCO-371, 2,4-Imidazolidinedione, 1-(3,5-dimethyl-4-(2-((4-oxo-2-(4-(trifluoromethoxy)phenyl)-1,3,8-triazaspiro(4.5)dec-1-en-8-yl)sulfonyl)ethyl)phenyl)-5,5-dimethyl-

Quick Database Links

Gene Symbol

Thyroid hormone receptor(THR)