Phlorizin

SKU: orb1304840

Description

Phlorizin is a natural, non-selective SGLT inhibitor isolated from apple, exhibiting inhibitory activity against hSGLT1 (Ki=300 nM) and hSGLT2 (Ki=39 nM). It is widely used in research to study glucose transport mechanisms in renal physiology and diabetes, both in vitro and in animal models.

Research Area

Pharmacology & Drug Discovery

Key Properties

• CAS Number: 60-81-1
• MW: 436.41
• Purity: 98.00% (May vary between batches)
• Formula: C₂₁H₂₄O₁₀
• SMILES: C(CCC1=CC=C(O)C=C1)(=O)C2=C(O[C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O)C=C(O)C=C2O
• Target: SGLT,ATPase
• Solubility: DMSO:118 mg/mL (270.39 mM);Ethanol:43.6 mg/mL (99.91 mM);10% DMSO+40% PEG300+5% Tween 80+45% Saline:4 mg/mL (9.17 mM);H2O:< 1 mg/mL (insoluble or slightly soluble)

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

inhibit, NSC 2833, Na+/K+ ATPase, NSC2833, NSC-2833, Floridzin, Inhibitor, hSGLT1, hSGLT2, Sodium potassium pump, Sodium-dependent glucose cotransporters, Phlorizin, Phloridzin, SGLT

Quick Database Links

Gene Symbol

SGLT,ATPase