Pifithrin-β hydrobromide

SKU: orb1303972

Description

Pifithrin-β hydrobromide is a cell-permeable inhibitor of p53 that reversibly blocks its transcriptional activity and apoptosis. It functions as an aryl hydrocarbon receptor (AHR) agonist and is applied in research on neuroprotection, cancer therapy side-effects, and stem cell biology, utilizing both in vivo stroke models and in vitro assays.

Research Area

Cell Biology

Key Properties

• CAS Number: 511296-88-1
• MW: 349.29
• Purity: 99.24% (May vary between batches)
• Formula: C₁₆H₁₇BrN₂S
• SMILES: Br.Cc1ccc(cc1)-c1cn2c3CCCCc3sc2n1
• Target: p53,Ferroptosis,MDM-2/p53
• Solubility: DMSO:13.75 mg/mL (39.37 mM);10% DMSO+40% PEG300+5% Tween 80+45% Saline:1 mg/mL (2.86 mM)

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Pifithrin β hydrobromide, Pifithrin-b, Pifithrin-b Hydrobromide, Pifithrin-beta, Pifithrin-beta Hydrobromide, Pifithrin-β, Pifithrinβ hydrobromide, Pifithrin-β Hydrobromide, PFT-b, PFT-beta, PFT-β, PFT b, PFT beta, PFT β, PFT β (hydrobromide), MDM-2/p53, Ferroptosis, p53, Cyclic PFT-a, Cyclic PFT-alpha, Cyclic PFT-α, Cyclic PFT-α, Cyclic Pifithrin-a Hydrobromide, Cyclic Pifithrin-alpha Hydrobromide, Cyclic Pifithrin-α, Cyclic Pifithrin-α hydrobromide, Cyclic Pifithrin-α hydrobromide

Quick Database Links

Gene Symbol

p53,Ferroptosis,MDM-2/p53