Pilaralisib analogue

SKU: orb1305574

Description

This compound is a selective, reversible inhibitor targeting the class I PI3K isoforms α, δ, and γ. It is a research tool used in vitro and in vivo to study PI3K pathway biology in areas such as oncology and immunology.

Research Area

Cell Biology, Molecular Biology, Signal Transduction

Key Properties

• CAS Number: 956958-53-5
• MW: 448.52
• Purity: 99.30% (May vary between batches)
• Formula: C₂₁H₁₆N₆O₂S₂
• SMILES: Cc1ccc(cc1)S(=O)(=O)Nc1nc2ccccc2nc1Nc1ccc2nsnc2c1
• Target: Apoptosis,DNA-PK,PI3K
• Solubility: H2O:< 1 mg/mL (insoluble or slightly soluble);DMSO:22.45 mg/mL (50.05 mM);Ethanol:< 1 mg/mL (insoluble or slightly soluble);10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (4.46 mM)

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

SAR245408, SAR-245408, SAR 245408, Phosphoinositide 3-kinase, PI3Kδ, PI3Kγ, PI3Kβ, PI3Kα, PI3K, Pilaralisib analogue, XL147 analogue, inhibit, Inhibitor, Apoptosis, DNA-PK, DNAPK

Quick Database Links

Gene Symbol

Apoptosis,DNA-PK,PI3K