Pimitespib

SKU: orb1307700

Description

Pimitespib (TAS-116) is a potent and selective ATP-competitive inhibitor targeting both HSP90α and HSP90β isoforms. It has demonstrated antitumor activity in preclinical models, supporting its research use in oncology for investigating HSP90's role in protein folding and cancer cell survival.

Research Area

Metabolism Research, Signal Transduction

Key Properties

• CAS Number: 1260533-36-5
• MW: 454.53
• Purity: 99.22% (May vary between batches)
• Formula: C₂₅H₂₆N₈O
• SMILES: CCc1cc(ccc1-n1nc(C(C)C)c2c(ccnc12)-n1cnc(c1)-c1cnn(C)c1)C(N)=O
• Target: HSP
• Solubility: 10% DMSO+40% PEG300+5% Tween 80+45% Saline:4 mg/mL (8.8 mM);DMSO:50 mg/mL (110 mM)

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Heat shock proteins, Inhibitor, HSP, HSP90α, HSP90β, inhibit, Pimitespib, TAS 116, TAS116, TAS-116

Quick Database Links

Gene Symbol

HSP