Pioglitazone

SKU: orb1310828

Description

Pioglitazone is a potent and selective PPARγ agonist with EC50 values of 0.93 μM (human) and 0.99 μM (mouse). This orally active small molecule is widely used in diabetes research for in vitro mechanistic studies and in vivo models of insulin resistance and glucose homeostasis.

Research Area

Cell Biology, Metabolism Research, Molecular Biology, Pharmacology & Drug Discovery

Key Properties

• CAS Number: 111025-46-8
• MW: 356.44
• Purity: 95.00% (May vary between batches)
• Formula: C₁₉H₂₀N₂O₃S
• SMILES: C(C1C(=O)NC(=O)S1)C2=CC=C(OCCC3=CC=C(CC)C=N3)C=C2
• Target: PPAR,Ferroptosis
• Solubility: 10% DMSO+90% Corn Oil:2 mg/mL (5.61 mM);DMSO:28.8 mg/mL (80.8 mM);Ethanol:< 1 mg/mL (insoluble or slightly soluble);H2O:< 1 mg/mL (insoluble or slightly soluble)

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Pioglitazone, PPARγ, PPAR, Peroxisome proliferator-activated receptors, U72107, U-72107, U 72107, inhibit, ligand-binding, Ferroptosis, Inhibitor, diabete, domain, blood glucose

Quick Database Links

Gene Symbol

PPAR,Ferroptosis