Piperonylic acid

SKU: orb1296953

Description

Piperonylic acid is a natural trans-cinnamic acid analog featuring a methylenedioxy group. It acts as a selective mechanism-based inactivator of the CYP73A subfamily of P450 enzymes, making it a valuable chemical probe for studying phenylpropanoid metabolism in plant biochemistry research, both in vitro and in vivo.

Research Area

Cardiovascular Research, Immunology & Inflammation, Metabolism Research, Signal Transduction

Key Properties

• CAS Number: 94-53-1
• MW: 166.13
• Purity: 99.93% (May vary between batches)
• Formula: C₈H₆O₄
• SMILES: OC(=O)C1=CC2=C(OCO2)C=C1
• Target: IGF-1R,EGFR,Cytochromes P450,Interleukin
• Solubility: DMSO:55 mg/mL (331.07 mM);10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (12.04 mM)

Storage & Handling

• Storage: Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Piperonylic acid, plant, tobacco, virus, 2H-1,3-benzodioxole-5-carboxylic acid, Cytochrome P450, CYPs, CYP73A, formation, mosaic, Inhibitor, inactivator, inhibit, natural, mimic, quasi-irreversible, P450s

Quick Database Links

Gene Symbol

IGF-1R,EGFR,Cytochromes P450,Interleukin