Ponesimod

SKU: orb1304376

Description

Ponesimod (ACT-128800) is a selective, orally active S1P1 receptor agonist that functions as an immunomodulator. It is used in research to investigate mechanisms of lymphocyte trafficking and has been studied in models of autoimmune diseases such as multiple sclerosis.

Research Area

Pharmacology & Drug Discovery

Key Properties

• CAS Number: 854107-55-4
• MW: 460.97
• Purity: 98.01% (May vary between batches)
• Formula: C₂₃H₂₅ClN₂O₄S
• SMILES: CCC\N=C1/S\C(=C/c2ccc(OC[C@H](O)CO)c(Cl)c2)C(=O)N1c1ccccc1C
• Target: S1P Receptor,LPL Receptor
• Solubility: 10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (4.34 mM);DMSO:235 mg/mL (509.79 mM);Ethanol:92 mg/mL (199.58 mM)

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

ACT 128800, ACT128800, ACT-128800, Inhibitor, lymphocyte-mediated, Lysophospholipid Receptor, inhibit, inflammation, LPL, LPL Receptor, LPLReceptor, S1PReceptor, S1P Receptor, S1P1, Ponesimod

Quick Database Links

Gene Symbol

S1P Receptor,LPL Receptor