Pristimerin

SKU: orb1222785

Description

Pristimerin has anticancer activity , treatment with Pristimerin may be a potential strategy for the suppression of hypoxia-induced metastasis through the reversal of hypoxia-induced stem cell characteristics and EMT in cancer cells. Pristimerin down-regulates the expression of pro-inflammatory mediators through blocking of NF-κB activation by inhibiting interconnected ROS/IKK/NF-κB signaling pathways, can effectively inhibit both arthritic inflammation and cartilage and bone damage in the joints.

Key Properties

• CAS Number: 1258-84-0
• MW: 464.64
• Purity: >98% (HPLC)
• Formula: C₃₀H₄₀O₄
• SMILES: CC1=C(C(=O)C=C2C1=CC=C3C2(CCC4(C3(CCC5(C4CC(CC5)(C)C(=O)OC)C)C)C)C)O
• Target: Sirtuin
• Solubility: DMSO : 20 mg/mL 43.04 mM; H2O : < 0.1 mg/mL

Storage & Handling

• Storage: Storage temperature: -20°C. Stability: ≥ 2 years
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Pristimerin | Celastrol-methylether | UNII-28ZK7PR57S

Quick Database Links

Gene Symbol

Sirtuin