Prucalopride

SKU: orb1305339

Description

Prucalopride (R-93877) is a potent and selective agonist for the 5-HT4A and 5-HT4B receptors, exhibiting over 290-fold selectivity versus other 5-HT subtypes. It is widely used in gastrointestinal motility research, including in vitro receptor studies and in vivo models of colonic dysmotility and constipation.

Research Area

Cell Biology, Neuroscience, Pharmacology & Drug Discovery

Key Properties

• CAS Number: 179474-81-8
• MW: 367.87
• Purity: 99.99% (May vary between batches)
• Formula: C₁₈H₂₆ClN₃O₃
• SMILES: COCCCN1CCC(CC1)NC(=O)c1cc(Cl)c(N)c2CCOc12
• Target: Autophagy,5-HT Receptor,Apoptosis
• Solubility: DMSO:56 mg/mL (152.23 mM);H2O:< 1 mg/mL (insoluble or slightly soluble);Ethanol:36 mg/mL (97.86 mM)

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

pseudo-intestinal obstruction, Prucalopride, Serotonin Receptor, R 93877, R-93877, R93877, chronic constipation, A427, A549, 5-HT Receptor, 5-HT4A, 5-HT4B, 5HTReceptor, 5HT Receptor, 5-hydroxytryptamine Receptor, Inhibitor, Lung cancer, inhibit

Quick Database Links

Gene Symbol

Autophagy,5-HT Receptor,Apoptosis