Ramelteon

SKU: orb1308555

Description

Ramelteon (TAK-375) is a selective agonist for melatonin MT1 and MT2 receptors. It is widely used in sleep research to investigate circadian rhythm regulation and sleep-wake cycles in both in vitro binding assays and in vivo animal models of insomnia.

Research Area

Neuroscience, Pharmacology & Drug Discovery

Key Properties

• CAS Number: 196597-26-9
• MW: 259.34
• Purity: 97.21% (May vary between batches)
• Formula: C₁₆H₂₁NO₂
• SMILES: CCC(=O)NCC[C@@H]1CCc2ccc3OCCc3c12
• Target: Melatonin Receptor,MT Receptor
• Solubility: Ethanol:49 mg/mL (188.94 mM);DMSO:60 mg/mL (231.36 mM);10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (7.71 mM);H2O:< 1 mg/mL (insoluble or slightly soluble)

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

MTReceptor, MT2, MT2 receptor, MT1, MT receptor (chicken), MT Receptor, MT1 receptor, inhibit, next-morning residual effect, oral, insomnia, Inhibitor, MelatoninReceptor, Melatonin Receptor, discontinuation, TAK 375, TAK375, TAK-375, Ramelteon, withdrawal symptom, rebound insomnia

Quick Database Links

Gene Symbol

Melatonin Receptor,MT Receptor