RG13022

SKU: orb1304081

Description

RG13022 (Tyrphostin RG13022) is a selective epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor, exhibiting an IC50 of 4 μM against autophosphorylation. It is a valuable research tool for studying EGFR signaling pathways in cellular and biochemical assays.

Research Area

Cardiovascular Research, Signal Transduction

Key Properties

• CAS Number: 136831-48-6
• MW: 266.29
• Purity: 98.38% (May vary between batches)
• Formula: C₁₆H₁₄N₂O₂
• SMILES: COc1ccc(\C=C(\C#N)c2cccnc2)cc1OC
• Target: EGFR
• Solubility: DMSO:50 mg/mL (187.77 mM);10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (7.51 mM)

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

HER1, EGFR, Epidermal growth factor receptor, ErbB-1, inhibit, Inhibitor, RG 13022, RG13022, RG-13022, Tyrphostin RG 13022, Tyrphostin RG13022, Tyrphostin RG-13022

Quick Database Links

Gene Symbol

EGFR