RGFP966

SKU: orb1307511

Description

RGFP966 is a potent and selective HDAC3 inhibitor with an IC50 of 0.08 μM. It is widely used in research to investigate epigenetic mechanisms in neuroscience, oncology, and metabolic studies, with applications in both cellular and animal models.

Research Area

Epigenetics & Chromatin, Neuroscience

Key Properties

• CAS Number: 1357389-11-7
• MW: 362.40
• Purity: >98%
• Formula: C₂₁H₁₉FN₄O
• SMILES: Nc1cc(F)ccc1NC(=O)\C=C\c1cnn(C\C=C\c2ccccc2)c1
• Target: Protein deacetylase
• Solubility: Soluble in DMSO (up to 20 mg/ml)

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

RGFP 966, RGFP966, RGFP-966, Inhibitor, HDAC3, HDAC, Histone deacetylases, inhibit

Quick Database Links

Gene Symbol

Protein deacetylase

Rudy Matheson 1 & Kohei Chida 2 & Hui Lu 1,3 & Victoria Clendaniel 1 & Marc Fisher 4 & Ajith Thomas 5 & Eng H. Lo 6 & Magdy Selim 4 & Amjad Shehadah 4 Neuroprotective Effects of Selective Inhibition of Histone Deacetylase 3 in Experimental Stroke Ponatinib inhibitor, (2024)