RGX-104 hydrochloride

SKU: orb1302065

Description

RGX-104 hydrochloride (SB742881) is a synthetic Liver X Receptor (LXR) agonist. Its transcriptional activation of the ApoE gene underlies its immunomodulatory and potential anti-cancer properties, which have been investigated in both cellular assays and animal models of oncology and immunology.

Research Area

Metabolism Research

Key Properties

• CAS Number: 610318-03-1
• MW: 632.54
• Purity: 98.56% (May vary between batches)
• Formula: C₃₄H₃₄Cl₂F₃NO₃
• SMILES: Cl.C[C@H](CCOc1cccc(CC(O)=O)c1)N(CC(c1ccccc1)c1ccccc1)Cc1cccc(c1Cl)C(F)(F)F
• Target: Liver X Receptor
• Solubility: DMSO:115 mg/mL (181.81 mM);10% DMSO+40% PEG300+5% Tween 80+45% Saline:3.3 mg/mL (5.22 mM)

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Inhibitor, LXR, inhibit, Liver X receptor, Liver X Receptor, LiverXReceptor, SB742881, SB-742881, SB 742881, RGX 104, RGX 104 Hydrochloride, RGX 104 hydrochloride, RGX104, RGX-104, RGX-104 HCl, RGX104 Hydrochloride, RGX104 hydrochloride, RGX-104 Hydrochloride

Quick Database Links

Gene Symbol

Liver X Receptor