Ridaforolimus

SKU: orb1300859

Description

Ridaforolimus is a non-prodrug rapamycin analog that acts as a potent and selective mTOR kinase inhibitor. It is used in cancer research to study proliferation and survival pathways, with applications in both in vitro cell-based assays and in vivo tumor models.

Research Area

Cell Biology, Infectious Disease & Virology, Pharmacology & Drug Discovery, Signal Transduction

Key Properties

• CAS Number: 572924-54-0
• MW: 990.21
• Purity: 90.00% (May vary between batches)
• Formula: C₅₃H₈₄NO₁₄P
• SMILES: [H][C@@]12CC[C@@H](C)[C@@](O)(O1)C(=O)C(=O)N1CCCC[C@@]1([H])C(=O)O[C@@]([H])(CC(=O)[C@H](C)\C=C(C)\[C@@H](O)[C@@H](OC)C(=O)[C@H](C)C[C@H](C)\C=C\C=C\C=C(C)\[C@H](C2)OC)[C@H](C)C[C@@H]1CC[C@@H](OP(C)(C)=O)[C@@H](C1)OC
• Target: mTOR,Autophagy,Antibacterial
• Solubility: Ethanol:< 1 mg/mL (insoluble or slightly soluble);DMSO:182 mg/mL (183.8 mM);H2O:< 1 mg/mL (insoluble or slightly soluble);10% DMSO+40% PEG300+5% Tween 80+45% Saline:4 mg/mL (4.04 mM)

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Ridaforolimus, MK8669, MK-8669, MK 8669, inhibit, mTOR, Mammalian target of Rapamycin, Inhibitor, AP 23573, AP23573, AP-23573, Autophagy, Deforolimus

Quick Database Links

Gene Symbol

mTOR,Autophagy,Antibacterial