Riociguat

SKU: orb1300303

Description

Riociguat (BAY 632521) is a soluble guanylate cyclase (sGC) stimulator used in research for severe pulmonary arterial hypertension. It induces vasodilation by enhancing cGMP signaling and is applied in both in vitro mechanistic studies and in vivo animal models of pulmonary hypertension.

Research Area

Pharmacology & Drug Discovery

Key Properties

• CAS Number: 625115-55-1
• MW: 422.42
• Purity: 99.28% (May vary between batches)
• Formula: C₂₀H₁₉FN₈O₂
• SMILES: COC(=O)N(C)c1c(N)nc(nc1N)-c1nn(Cc2ccccc2F)c2ncccc12
• Target: Guanylate cyclase
• Solubility: Ethanol:< 1 mg/mL (insoluble or slightly soluble);10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (4.73 mM);DMSO:40.83 mg/mL (96.66 mM);H2O:< 1 mg/mL (insoluble or slightly soluble)

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

BAY632521, BAY-632521, BAY 632521, guanylate cyclase, Guanylatecyclase, Guanylate Cyclase, Guanylate cyclase, Inhibitor, inhibit, Riociguat

Quick Database Links

Gene Symbol

Guanylate cyclase