RORγt Inverse agonist 6

SKU: orb1309153

Description

RORγt Inverse agonist 6 is a potent synthetic ligand that acts as an inverse agonist of the RORγt nuclear receptor. It is a valuable research tool for studying Th17 cell biology and has demonstrated utility in both cellular assays and animal models of autoimmune diseases.

Research Area

Metabolism Research, Pharmacology & Drug Discovery

Key Properties

• CAS Number: 1887161-80-9
• MW: 565.02
• Purity: 98.65% (May vary between batches)
• Formula: C₂₈H₂₉ClN₆O₅
• SMILES: CC(C)n1c2ccc(NC(=O)N3CCO[C@H](C3)C(=O)Nc3ccc(C#N)c(Cl)c3)cc2c(=O)n(CC2CC2)c1=O
• Target: ROR
• Solubility: 10% DMSO+90% Corn Oil:2 mg/mL (3.54 mM);DMSO:45 mg/mL (79.64 mM)

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

RAR-related orphan receptor, RORgammat Inverse agonist 6, ROR, RORrt Inverse agonist 6, RORγt, RORγt Inverse agonist 6, RORγt Inverse agonist6, RORγt Inverse agonist-6, inhibit, Inhibitor

Quick Database Links

Gene Symbol

ROR