Rosuvastatin calcium

SKU: orb1308393

Description

Rosuvastatin calcium is a potent, selective, and competitive inhibitor of HMG-CoA reductase, exhibiting significant antilipidemic activity. It is widely used in research to study cholesterol biosynthesis and atherosclerosis in both in vitro enzymatic assays and in vivo animal models.

Research Area

Cell Biology, Infectious Disease & Virology, Metabolism Research, Pharmacology & Drug Discovery

Key Properties

• CAS Number: 147098-20-2
• MW: 1001.14
• Purity: 98.21% (May vary between batches)
• Formula: 2(C₂₂H₂₇FN₃O₆S)Ca
• SMILES: [Ca++].CC(C)C1=C(\C=C\[C@@H](O)C[C@@H](O)CC([O-])=O)C(=NC(=N1)N(C)S(C)(=O)=O)C1=CC=C(F)C=C1.CC(C)C1=C(\C=C\[C@@H](O)C[C@@H](O)CC([O-])=O)C(=NC(=N1)N(C)S(C)(=O)=O)C1=CC=C(F)C=C1
• Target: HMG-CoA Reductase,Antibacterial,Potassium Channel,Autophagy
• Solubility: DMSO:123 mg/mL (122.86 mM);10% DMSO+40% PEG300+5% Tween 80+45% Saline:4 mg/mL (4 mM)

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

low-density, lipoprotein, HMGCoA Reductase, HMGCoAReductase, HMG-CoA reductase, HMGCR, Hsp70, action, APDs, Autophagy, durations, cholesterol, cardiac, Rosuvastatin, Rosuvastatin calcium, Rosuvastatin hemicalcium, repolarization, ZD-4522, ZD 4522, ZD 4522 Calcium, QTc, Potassium Channel, PotassiumChannel, potential, triglycerides

Quick Database Links

Gene Symbol

HMG-CoA Reductase,Antibacterial,Potassium Channel,Autophagy