Rotigotine-

SKU: orb1300587

Description

Rotigotine (N-0923) is a non-ergot dopamine agonist used to treat Parkinson's disease and restless legs syndrome via a transdermal patch. It is employed in neuroscience research to study dopaminergic pathways in both in vitro receptor binding assays and in vivo models of movement disorders, with no significant association with drug-induced liver injury.

Research Area

Neuroscience, Pharmacology & Drug Discovery

Key Properties

• CAS Number: 99755-59-6
• MW: 315.47
• Purity: 98.08% (May vary between batches)
• Formula: C₁₉H₂₅NOS
• SMILES: OC1=C2C(C[C@@H](N(CCC3=CC=CS3)CCC)CC2)=CC=C1
• Target: 5-HT Receptor,Dopamine Receptor,Adrenergic Receptor
• Solubility: 10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (6.34 mM);H2O:< 1 mg/mL (insoluble or slightly soluble);DMSO:75 mg/mL (237.74 mM);Ethanol:59 mg/mL (187.02 mM)

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

5-HT1A, 5-HT Receptor, AdrenergicReceptor, Adrenergic Receptor, 5HTReceptor, 5-hydroxytryptamine Receptor, 5HT Receptor, D2, D3, dopamine, Dopamine, Dopamine Receptor, DopamineReceptor, Beta Receptor, Inhibitor, N 0437, N 0923, inhibit, N0437, N-0437, N0923, N-0923, Neupro, α2B-adrenergic, Rotigotine, Rotigotine-, SPM 962, SPM962, SPM-962, Serotonin Receptor, receptor

Quick Database Links

Gene Symbol

5-HT Receptor,Dopamine Receptor,Adrenergic Receptor