Rottlerin

SKU: orb1307775

Description

Rottlerin (NSC-56346), a natural compound from Mallotus philippinensis, is a selective PKCδ inhibitor (IC50 3-6 μM) that induces apoptosis through caspase-3 activation. It is widely used in biochemical research to study PKC isoform-specific signaling and programmed cell death in various cancer and cellular models.

Research Area

Cell Biology, Neuroscience

Key Properties

• CAS Number: 82-08-6
• MW: 516.65
• Purity: >96%
• Formula: C₃₀H₂₈O₈
• SMILES: CC(=O)c1c(O)c(C)c(O)c(Cc2c(O)c3C=CC(C)(C)Oc3c(C(=O)\C=C\c3ccccc3)c2O)c1O
• Target: PKC,PKA,HIV Protease,CaMK,Apoptosis,Autophagy
• Solubility: Soluble in DMSO (up to 50 mg/ml).

Storage & Handling

• Storage: RT
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

CKII, CaM kinase III, Autophagy, Apoptosis, Mallotoxin, HIV, HIVProtease, HIV Protease, Human immunodeficiency virus, inhibit, NSC56346, NSC-56346, NSC 56346, NSC 94525, Inhibitor, NSC94525, NSC-94525, PKA, PKC, PKCα, PKCβ, PKCγ, PKCδ, PKCε, PKCζ, PKCη, Protein kinase C, Rottlerin

Quick Database Links

Gene Symbol

PKC,PKA,HIV Protease,CaMK,Apoptosis,Autophagy