Rotundine

SKU: orb1300586

Description

Rotundine (L-THP, Gindarine) is a selective dopamine D1 receptor antagonist with an IC50 of 166 nM. It is widely used in neuroscience research to study dopaminergic pathways, with applications in both in vitro binding assays and in vivo behavioral models.

Research Area

Neuroscience, Pharmacology & Drug Discovery

Key Properties

• CAS Number: 483-14-7
• MW: 355.43
• Purity: 99.73% (May vary between batches)
• Formula: C₂₁H₂₅NO₄
• SMILES: O(C)C=1C=C2[C@]3(N(CC=4C(C3)=CC=C(OC)C4OC)CCC2=CC1OC)[H]
• Target: Dopamine Receptor,5-HT Receptor
• Solubility: Ethanol:< 1 mg/mL (insoluble or slightly soluble);H2O:< 1 mg/mL (insoluble or slightly soluble);DMSO:55 mg/mL (154.74 mM)

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

5-HT1A, 5-HT Receptor, 5HT Receptor, 5HTReceptor, 5-hydroxytryptamine Receptor, (-)-Tetrahydropalmatine, Dopamine, DopamineReceptor, Dopamine Receptor, D1, D2, D3, Caseanine, Gindarine, inhibit, Inhibitor, L-Tetrahydropalmatine, Serotonin Receptor, Rotundine, Tetrahydropalmatine

Quick Database Links

Gene Symbol

Dopamine Receptor,5-HT Receptor