Rubiadin-1-methyl ether

SKU: orb1303033

Description

Rubiadin-1-methyl ether is a natural compound that suppresses osteoclast-mediated bone resorption. It functions by inhibiting NF-κB pathway activation, specifically blocking p65 phosphorylation, IκBα degradation, and p65 nuclear translocation. This mechanism supports its research application in studying bone metabolism disorders such as osteoporosis in cellular models.

Research Area

Infectious Disease & Virology, Signal Transduction

Key Properties

• CAS Number: 7460-43-7
• MW: 268.26
• Purity: 97.79% (May vary between batches)
• Formula: C₁₆H₁₂O₄
• SMILES: COc1c(C)c(O)cc2C(=O)c3ccccc3C(=O)c12
• Target: NF-κB,Anti-infection
• Solubility: DMSO:2.69 mg/mL (10.03 mM)

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Rubiadin 1 methyl ether, Rubiadin 1-methyl ether, Rubiadin1methyl ether, Rubiadin-1-methyl ether, Nuclear factor-kappaB, Nuclear factor-κB, NFκB, NF-kB, NFkB, NF-κB, inhibit, Inhibitor, Antifection, Anti-infection, Antiinfection

Quick Database Links

Gene Symbol

NF-κB,Anti-infection